The Secretariat handles the day-to-day business and administration of the Commission and implements its decisions (monitoring and evaluation of projects, editing reports and publications, producing and publishing the periodical on women's issues, organizing events). It maintains contact and exchanges information with government agencies and institutions, with women's and human rights organizations and with researchers. The Secretariat also acts as a point of contact for the media and the general public.
The Director of the Secretariat attends meetings of the Plenary and the Executive Committee in an advisory capacity.